reviewAdvanced ScienceMar 6, 2025GOLD OA

Applications of Artificial Intelligence in Drug Repurposing

Chinese Academy of Medical Sciences & Peking Union Medical College · Suzhou Institute of Systems Medicine · +4 more institutions

PubMed
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Abstract

Drug repurposing identifies new therapeutic uses for the existing drugs originally developed for different indications, aiming at capitalizing on the established safety and efficacy profiles of known drugs. Thus, it is beneficial to bypass of early stages of drug development, and to reduction of the time and cost associated with bringing new therapies to market. Traditional experimental methods are often time-consuming and expensive, making artificial intelligence (AI) a promising alternative due to its lower cost, computational advantages, and ability to uncover hidden patterns. This review focuses on the availability of AI algorithms in drug development, and their positive and specific roles in revealing…

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