articleNitrogenMar 12, 2025GOLD OA

Harnessing Nitrogen-Fixing Cyanobacteria for Sustainable Agriculture: Opportunities, Challenges, and Implications for Food Security

South Dakota State University · Abdul Wali Khan University Mardan

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Abstract

Nitrogen, an essential element for plant growth and food production, presents significant challenges in agriculture due to the environmental consequences of synthetic nitrogen fertilizers. This review explores the potential of nitrogen-fixing cyanobacteria as a sustainable alternative for agricultural nitrogen fertilization. The molecular mechanisms underlying nitrogen fixation in cyanobacteria, including key genes such as nif and related biochemical pathways, are examined in detail. Biotechnological approaches for utilizing nitrogen-fixing cyanobacteria as biofertilizers are discussed, alongside strategies for genetic engineering to improve nitrogen fixation efficiency. The review further evaluates the impact…

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