Biomimetic structural design in 3D-printed scaffolds for bone tissue engineering
Shanghai University · Shanghai Jiao Tong University · +3 more institutions
Abstract
The rising prevalence of bone diseases in an aging population underscores the urgent need for innovative and clinically translatable solutions in bone tissue engineering. While significant progress has been made in refining the chemical properties of biomaterials, the structural design of scaffolds-a critical determinant of repair success-remains comparatively underexplored. Structural parameters such as porosity, pore size, and interconnectivity are not only essential for achieving mechanical stability but also pivotal in regulating biological processes, including vascularization, osteogenesis, and immune modulation. This review systematically categorizes scaffold architectures documented in the literature…
Citation impact
- FWCI
- 30.66
- Percentile
- 100%
- References
- 260
Authors
7Topics & keywords
- Tissue engineering
- 3d printed
- 3D printing
- Materials science
- Biomedical engineering
- Engineering
- Composite material