reviewEuropean Journal of Medicinal ChemistryMar 19, 2025HYBRID OA

Mechanistic study of cancer drug delivery: Current techniques, limitations, and future prospects

King Fahd University of Petroleum and Minerals · Qatar University · +1 more institution

PubMed
Indexed incrossrefpubmed

Abstract

Cancer drug delivery remains a critical challenge with systemic toxicity, poor drug bioavailability, and a lack of effective targeting. Overcoming these barriers is essential for improving treatment efficacy and patient outcomes. This review discusses current drug delivery techniques that reshape cancer therapy by offering precise, controlled-release tailored to tumor-specific features. Innovations in nanotechnology, immunotherapy, and gene therapy enable interventions at molecular and cellular levels. Radiomics and pathomics integrate high-dimensional data to optimize diagnostics and treatment planning. Combination therapy addresses the complexities of tumor heterogeneity by synergizing multiple agents within…

Citation impact

68
total citations
FWCI
31.74
Percentile
100%
References
196
Citations per year

Authors

7

Topics & keywords

Keywords
  • Chemistry
  • Current (fluid)
  • Cancer
  • Drug
  • Drug delivery
  • Pharmacology
  • Biochemical engineering
  • Risk analysis (engineering)
UN Sustainable Development Goals
  • Good health and well-being
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