articleGastroenterologyMar 19, 2025HYBRID OA

Machine Learning and Artificial Intelligence in the Multi-Omics Approach to Gut Microbiota

University of Naples Federico II · Federico II University Hospital

PubMed
Indexed incrossrefpubmed

Abstract

The gut microbiome is involved in human health and disease, and its comprehensive understanding is necessary to exploit it as a diagnostic or therapeutic tool. Multi-omics approaches, including metagenomics, metatranscriptomics, metabolomics, and metaproteomics, enable depiction of the gut microbial ecosystem's complexity. However, these tools generate a large data stream in which integration is needed to produce clinically useful readouts, but, in turn, might be difficult to carry out with conventional statistical methods. Artificial intelligence and machine learning have been increasingly applied to multi-omics datasets in several conditions associated with microbiome disruption, from chronic disorders to…

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62
total citations
FWCI
38.41
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100%
References
157
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Authors

4

Topics & keywords

Keywords
  • Gut flora
  • Artificial intelligence
  • Omics
  • Computer science
  • Computational biology
  • Machine learning
  • Biology
  • Bioinformatics
UN Sustainable Development Goals
  • Zero hunger
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