3D tumor cultures for drug resistance and screening development in clinical applications
Liuzhou Maternal and Child Health Hospital · Consejo Superior de Investigaciones Científicas · +3 more institutions
Abstract
Tumor drug resistance presents a growing challenge in medical practice, particularly during anti-cancer therapies, where the emergence of drug-resistant cancer cells significantly complicates clinical treatment. In recent years, three-dimensional (3D) tumor culture technology, which more effectively simulates the in vivo physiological environment, has gained increasing attention in tumor drug resistance research and clinical applications. By mimicking the in vivo cellular microenvironment, 3D tumor culture technology not only recapitulates cell-cell interactions but also more faithfully reproduces the biological effects of therapeutic agents. Consequently, 3D tumor culture technology is emerging as a crucial…
Citation impact
- FWCI
- 25.63
- Percentile
- 100%
- References
- 102
Authors
5Topics & keywords
- Biology
- Drug resistance
- Drug development
- Drug
- Computational biology
- Cancer research
- Genetics
- Pharmacology