A systematic review with a Burden of Proof meta-analysis of health effects of long-term ambient fine particulate matter (PM2.5) exposure on dementia
University of Washington · Institute for Health Metrics and Evaluation · +4 more institutions
Abstract
Abstract Previous studies have indicated increased dementia risk associated with fine particulate matter (PM 2.5 ) exposure; however, the findings are inconsistent. In this systematic review, we assessed the association between long-term PM 2.5 exposure and dementia outcomes using the Burden of Proof meta-analytic framework, which relaxes log-linear assumptions to better characterize relative risk functions and quantify unexplained between-study heterogeneity (PROSPERO, ID CRD42023421869). Here we report a meta-analysis of 28 longitudinal cohort studies published up to June 2023 that investigated long-term PM 2.5 exposure and dementia outcomes. We derived risk–outcome scores (ROSs), highly conservative…
Citation impact
- FWCI
- 40.79
- Percentile
- 100%
- References
- 86
Authors
16- XHXinmei HuangCorresponding
University of Washington, Institute for Health Metrics and Evaluation
- JDJaimie D Steinmetz
University of Washington, Institute for Health Metrics and Evaluation
- EKElizabeth K. Marsh
University of Washington, Institute for Health Metrics and Evaluation
- AYAleksandr Y. Aravkin
University of Washington, Institute for Health Metrics and Evaluation
- CACharlie Ashbaugh
University of Washington, Institute for Health Metrics and Evaluation
Topics & keywords
- Dementia
- Meta-analysis
- Relative risk
- Vascular dementia
- Medicine
- Percentile
- Cohort study
- Cohort
- Good health and well-being