reviewGelsMar 23, 2025GOLD OA

Hydrogel-Based Biointerfaces: Recent Advances, Challenges, and Future Directions in Human–Machine Integration

Pukyong National University

PubMed
Indexed incrossrefdoajpubmed

Abstract

Human-machine interfacing (HMI) has emerged as a critical technology in healthcare, robotics, and wearable electronics, with hydrogels offering unique advantages as multifunctional materials that seamlessly connect biological systems with electronic devices. This review provides a detailed examination of recent advancements in hydrogel design, focusing on their properties and potential applications in HMI. We explore the key characteristics such as biocompatibility, mechanical flexibility, and responsiveness, which are essential for effective and long-term integration with biological tissues. Additionally, we highlight innovations in conductive hydrogels, hybrid and composite materials, and fabrication…

Citation impact

56
total citations
FWCI
29.73
Percentile
100%
References
266
Citations per year

Authors

4

Topics & keywords

Keywords
  • Self-healing hydrogels
  • Flexibility (engineering)
  • Nanotechnology
  • Computer science
  • Wearable technology
  • Wearable computer
  • Human–computer interaction
  • Materials science
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Funding