reviewTranslational Lung Cancer ResearchMar 1, 2025DIAMOND OA

Recent advancements in lung cancer research: a narrative review

FTFuk TangHYHeylie Y. T. WongPSPhyllis S. W. TsangMYMabel YauSYShing Yau Tam

Tung Wah College

PubMed
Indexed incrossrefpubmed

Abstract

Methods

A comprehensive literature review was performed utilizing the PubMed Central database to identify recent studies relevant to lung cancer. This review synthesizes findings from various research articles to provide a cohesive summary of advancements in the field. Key Content and Findings: In the past decade, notable progress has been achieved in lung cancer research, particularly concerning diagnostics and treatment strategies. Novel therapeutic approaches, including immunotherapy and genomic-targeted therapies, have demonstrated promising results. Understanding the tumor microenvironment (TME) and the role of T lymphocytes has become crucial for developing effective treatments. Additionally, advancements in immune checkpoint inhibitors (ICIs) have shown potential in enhancing patient outcomes. Improvements in tumor detection technologies are also anticipated to facilitate earlier diagnosis, ultimately contributing to better survival rates.

Conclusions

Significant strides have been made in lung cancer research over the last ten years, particularly in diagnostics and treatment methodologies. Future research should prioritize exploring the TME, the function of T lymphocytes, and the efficacy of ICIs while continuing to innovate in tumor detection technologies. Such efforts are essential for enhancing treatment outcomes and improving the overall quality of life for lung cancer patients.

Citation impact

49
total citations
FWCI
38.88
Percentile
100%
References
1
Citations per year

Authors

10

Topics & keywords

Keywords
  • Medicine
  • Lung cancer
  • Narrative review
  • Narrative
  • Data science
  • Computational biology
  • Bioinformatics
  • Intensive care medicine
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