Routine Cerebral Embolic Protection during Transcatheter Aortic-Valve Implantation
John Radcliffe Hospital · University of Oxford · +51 more institutions
Abstract
Transcatheter aortic-valve implantation (TAVI) is associated with procedure-related stroke. Cerebral embolic protection (CEP) devices may reduce embolization to the cerebral circulation and hence the incidence of stroke.
We conducted a randomized, controlled trial across 33 centers in the United Kingdom. We randomly assigned 7635 participants with aortic stenosis in a 1:1 ratio to undergo TAVI with a CEP device (CEP group) or TAVI without a CEP device (control group). The primary outcome was stroke within 72 hours after TAVI or before discharge from the hospital (if discharge occurred sooner).
Citation impact
- FWCI
- 72.55
- Percentile
- 100%
- References
- 15
Authors
46- RKRajesh KharbandaCorresponding
John Radcliffe Hospital, University of Oxford, Oxford BioMedica (United Kingdom)
- JKJames Kennedy
University of Oxford
- ZJZahra Jamal
University of London, London School of Hygiene & Tropical Medicine
- MCMatthew C. Dodd
University of London, London School of Hygiene & Tropical Medicine
- RERichard Evans
University of London, London School of Hygiene & Tropical Medicine
Topics & keywords
- Cerebral embolism
- Cardiology
- Medicine
- Internal medicine
- Embolic stroke
- Embolism
- Ischemia
- Ischemic stroke
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