Diagnostic accuracy of plasma p‐tau217/Aβ42 for Alzheimer's disease in clinical and community cohorts

Wang, Jun; Huang, Shan; Lan, Guoyu; Lai, Yujie; Wang, Qinghua; Chen, Yang; Xiao, Zhong‐Song; Chen, X.; Bu, Xian‐Le; Liu, Yuhui; Zeng, Fan; Zhang, Laihong; Li, Anqi; Cai, Yue; Sun, Pan; He, Zhengbo; Doré, Vincent; Fripp, Jürgen; Bourgeat, Pierrick; Chen, Qin; Yu, Jin‐Tai; Tang, Yi; Zetterberg, Henrik; Masters, Colin L.; Guo, Tengfei; Wang, Yan‐Jiang

doi:10.1002/alz.70038

articleAlzheimer s & DementiaMar 1, 2025HYBRID OA

Diagnostic accuracy of plasma p‐tau217/Aβ42 for Alzheimer's disease in clinical and community cohorts

JWJun Wang SHShan Huang GLGuoyu Lan YLYujie Lai QWQinghua Wang

Army Medical University · Daping Hospital · +18 more institutions

PubMed

Indexed incrossrefpubmed

Abstract

Introduction

This study was undertaken to evaluate the diagnostic performance of a novel plasma phosphorylated tau (p-tau) 217/amyloid beta (Aβ) 42 ratio test for Alzheimer's disease (AD).

Methods

The diagnostic performance of the Lumipulse G plasma p-tau217/Aβ42 ratio was evaluated using Aβ and tau positron emission tomography (PET) as reference standards in a clinic cohort (n = 391) and a community cohort (n = 121).

Citation impact

63

total citations

FWCI: 68.19
Percentile: 100%
References: 49

Citations per year

Authors

26

Topics & keywords

Topics

Keywords

Disease
Medicine
Alzheimer's disease
Gerontology
Psychology
Internal medicine

No related works found for this paper.