reviewMolecular Nutrition & Food ResearchMar 30, 2025HYBRID OA

Immunomodulatory Effects of Omega‐3 Fatty Acids: Mechanistic Insights and Health Implications

Ankara University · Tata Institute of Fundamental Research · +2 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Omega-3 fatty acids play a significant role in immunomodulation, with nutrigenomic approaches highlighting their impact on gene expression related to immune responses. Research indicates that omega-3 fatty acids can modulate inflammatory pathways, potentially reducing chronic inflammation and enhancing immune function. This review discusses the intersection of nutrigenomics and nutriepigenomics, focusing on how omega-3 fatty acids influence gene expression, immune function, and overall health. The immune system is a complex network responsible for defending the body against pathogens and maintaining internal balance. Comprised of innate and adaptive immunity, the system involves various cells, tissues, and…

Citation impact

67
total citations
FWCI
58.76
Percentile
100%
References
218
Citations per year

Authors

4

Topics & keywords

Keywords
  • Docosahexaenoic acid
  • Immune system
  • Proinflammatory cytokine
  • Eicosapentaenoic acid
  • Polyunsaturated fatty acid
  • Inflammation
  • Nutrigenomics
  • Biology
UN Sustainable Development Goals
  • Good health and well-being
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