Graphene-Based Glucose Sensors with an Attomolar Limit of Detection

Diabetes mellitus, a prevalent metabolic disorder affecting hundreds of millions of people worldwide, demands continuous glucose monitoring for effective management. Current blood glucose monitoring methods, such as commercial glucometers, are accurate but are often perceived as uncomfortable. Motivated by the need for noninvasive, ultrasensitive alternatives, our study presents electrolyte-gated graphene field-effect transistors functionalized with glucose oxidase. We developed an optimized fabrication process that integrates a 32-transistor matrix within a miniaturized 1000 μm2 footprint, ensuring high device uniformity while enabling detection in 40 μL analyte volume. A comprehensive suite of…

• FP
  Fundação para a Ciência e a Tecnologia

  Award: DRI/India/0664/2020