reviewNature CommunicationsApr 2, 2025GOLD OA

Machine learning in point-of-care testing: innovations, challenges, and opportunities

University of California, Los Angeles · California NanoSystems Institute · +5 more institutions

PubMed
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Abstract

The landscape of diagnostic testing is undergoing a significant transformation, driven by the integration of artificial intelligence (AI) and machine learning (ML) into decentralized, rapid, and accessible sensor platforms for point-of-care testing (POCT). The COVID-19 pandemic has accelerated the shift from centralized laboratory testing but also catalyzed the development of next-generation POCT platforms that leverage ML to enhance the accuracy, sensitivity, and overall efficiency of point-of-care sensors. This Perspective explores how ML is being embedded into various POCT modalities, including lateral flow assays, vertical flow assays, nucleic acid amplification tests, and imaging-based sensors,…

Citation impact

160
total citations
FWCI
83.15
Percentile
100%
References
233
Citations per year

Authors

15

Topics & keywords

Keywords
  • Point-of-care testing
  • Computer science
  • Leverage (statistics)
  • Coronavirus disease 2019 (COVID-19)
  • Modalities
  • Health care
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
  • Point of care
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Funding