Advancing Gut Microbiome Research: The Shift from Metagenomics to Multi-Omics and Future Perspectives

Advancements in NGS technologies have significantly expanded the scope and efficiency of metagenomics, surpassing traditional culture-based methods (Fig. 2).These innovations enable multi-domain microbial analysis through advanced bioinformatics tools, long-read sequencing, single-cell omics, and enhanced culture-based techniques, facilitating deeper insights into microbial diversity, function, and host interactions.The integration of cutting-edge computational tools and experimental methodologies has enhanced microbiome research, enabling the discovery of novel microbes, metabolic pathways, and therapeutic targets. Multi-domain microbial analysis and advanced bioinformatics tools.Recent metagenomic research…

• MO
  Ministry of Trade, Industry and Energy

  Award: 20018770
• NR
  National Research Foundation of Korea

  Award: RS-2021-NR056579
• KN
  Korea National Institute of Health

  Award: 2024-ER2109-01