Early Ezetimibe Initiation After Myocardial Infarction Protects Against Later Cardiovascular Outcomes in the SWEDEHEART Registry

Leósdóttir, Margrét; Schubert, Jessica; Brandts, Julia; Gustafsson, Stefan; Cars, Thomas; Sundström, Johan; Jernberg, Tomas; Ray, Kausik K.; Hagström, Emil

doi:10.1016/j.jacc.2025.02.007

articleJournal of the American College of CardiologyApr 1, 2025HYBRID OA

Early Ezetimibe Initiation After Myocardial Infarction Protects Against Later Cardiovascular Outcomes in the SWEDEHEART Registry

MLMargrét Leósdóttir JSJessica Schubert JBJulia Brandts SGStefan Gustafsson TCThomas Cars

Malmö University · Skåne University Hospital · +5 more institutions

PubMed

Indexed incrossrefpubmed

Abstract

BACKGROUND: Combination lipid-lowering therapy (LLT) after myocardial infarction (MI) achieves lower low-density lipoprotein cholesterol (LDL-C) levels and better cardiovascular outcomes vs statin monotherapy. As a result, global guidelines recommend lower LDL-C but, paradoxically, advise treatment through a stepwise approach. Yet the need for combination therapy is inevitable as

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44

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FWCI: 70.26
Percentile: 100%
References: 40

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Topics & keywords

Topics

Keywords

Medicine
Ezetimibe
Myocardial infarction
Cardiology
Internal medicine
Cholesterol

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