reviewInternational Journal of NanomedicineApr 1, 2025GOLD OA

Research Progress of Bone Grafting: A Comprehensive Review

Dalian Medical University · Dalian University of Technology · +3 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Bone tissue, the second most transplanted tissue after blood, is utilized in over 2.2 million bone grafts annually to address various bone-related conditions including fractures, tumors, bone infections, scoliosis, congenital defects, osteoporosis, osteoarthritis, and osteogenesis imperfecta. According to incomplete statistics, $4.3 billion was spent on bone graft materials in 2015 alone, with projections suggesting this figure may reach $66 billion by 2026. The limited availability of autogenous bone graft considered the gold standard due to their three critical biological properties: osteoconduction, osteoinduction, and osteogenesis-alongside the increasing global aging population, may be contributing to…

Citation impact

42
total citations
FWCI
57.55
Percentile
100%
References
198
Citations per year

Authors

6

Topics & keywords

Keywords
  • Grafting
  • Bone grafting
  • Materials science
  • Nanotechnology
  • Medicine
  • Dentistry
  • Composite material
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