An Update: Enzymatic Synthesis for Industrial Applications
Universitätsmedizin Greifswald · Universität Greifswald · +5 more institutions
Abstract
Abstract Supported by rapid technological advancements, biocatalytic applications have matured into sustainable, scalable, and cost‐competitive alternatives to established chemical catalysis. This review presents the most recent examples of enzyme‐based solutions for the manufacturing of molecules with extended carbon–carbon frameworks and multiple stereogenic centers at commercial scale, including peptide building blocks, (rare) sugars, synthetic (oligo)nucleotides, and terpenoids, such as (–)‐Ambrox ® . Novel enzyme classes are highlighted along with their potential applications—the synthesis of DNA/RNA, the depolymerization of synthetic plastics, or fully enzymatic protection/deprotection schemes—pointing…
Citation impact
- FWCI
- 30.02
- Percentile
- 100%
- References
- 264
Authors
5- TBThomas Bayer
Universitätsmedizin Greifswald, Universität Greifswald, Leibniz Institute for Plasma Science and Technology
- SWShuke Wu
Huazhong Agricultural University
- RŠRadka Šnajdrová
Novartis (Switzerland), Novartis Institutes for BioMedical Research
- KBKai Baldenius
Neovii Biotech (Germany)
- UTUwe T. BornscheuerCorresponding
Universitätsmedizin Greifswald, Universität Greifswald, Leibniz Institute for Plasma Science and Technology
Topics & keywords
- Biocatalysis
- Biochemical engineering
- Scalability
- Depolymerization
- Diversification (marketing strategy)
- Stereocenter
- Nanotechnology
- Chemistry
- Industry, innovation and infrastructure