Self-Powered Thermoelectric Hydrogels Accelerate Wound Healing

Electrical stimulation (ES) serves as a biological cue that regulates critical cellular processes, including proliferation and migration, offering an effective approach to accelerating wound healing. Thermoelectrics, capable of generating electricity by exploiting the temperature difference between skin and the surrounding environment without external energy input, present a promising avenue for ES-based therapies. Herein, we developed Ag2Se@gelatin methacrylate (Ag2Se@GelMA) thermoelectric hydrogels with high room-temperature thermoelectric performance and employed them as self-powered ES devices for wound repair. Systematic in vivo and in vitro investigations elucidated their biological mechanisms for…

• NN
  National Natural Science Foundation of China

  Award: 82401145
• DO
  Department of Science and Technology of Sichuan Province

  Award: 2024NSFSC1621
• AR
  Australian Research Council
• FR
  Fundamental Research Funds for the Central Universities

  Award: YJ202242
• WC
  West China School of Stomatology, Sichuan University

  Award: QDJF2022-2