reviewACS NanoApr 18, 2025HYBRID OA

Stimuli-Responsive Nanomedicines for the Treatment of Non-cancer Related Inflammatory Diseases

Solvay (Belgium) · University of Padua

PubMed
Indexed incrossrefpubmed

Abstract

Nanomedicines offer a means to overcome the limitations associated with traditional drug dosage formulations by affording drug protection, enhanced drug bioavailability, and targeted drug delivery to affected sites. Inflamed tissues possess unique microenvironmental characteristics (including excessive reactive oxygen species, low pH levels, and hypoxia) that stimuli-responsive nanoparticles can employ as triggers to support on-demand delivery, enhanced accumulation, controlled release, and activation of anti-inflammatory drugs. Stimuli-responsive nanomedicines respond to physicochemical and pathological factors associated with diseased tissues to improve the specificity of drug delivery, overcome multidrug…

Citation impact

51
total citations
FWCI
23.80
Percentile
100%
References
256
Citations per year

Authors

3

Topics & keywords

Keywords
  • Cancer
  • Cancer treatment
  • Medicine
  • Nanotechnology
  • Materials science
  • Internal medicine
UN Sustainable Development Goals
  • Good health and well-being
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