Stimuli-Responsive Nanomedicines for the Treatment of Non-cancer Related Inflammatory Diseases
Solvay (Belgium) · University of Padua
Abstract
Nanomedicines offer a means to overcome the limitations associated with traditional drug dosage formulations by affording drug protection, enhanced drug bioavailability, and targeted drug delivery to affected sites. Inflamed tissues possess unique microenvironmental characteristics (including excessive reactive oxygen species, low pH levels, and hypoxia) that stimuli-responsive nanoparticles can employ as triggers to support on-demand delivery, enhanced accumulation, controlled release, and activation of anti-inflammatory drugs. Stimuli-responsive nanomedicines respond to physicochemical and pathological factors associated with diseased tissues to improve the specificity of drug delivery, overcome multidrug…
Citation impact
- FWCI
- 23.80
- Percentile
- 100%
- References
- 256
Authors
3Topics & keywords
- Cancer
- Cancer treatment
- Medicine
- Nanotechnology
- Materials science
- Internal medicine
- Good health and well-being