articleScientific ReportsApr 22, 2025GOLD OA

Ensemble learning with explainable AI for improved heart disease prediction based on multiple datasets

Woxsen School of Business · Galgotias University · +1 more institution

PubMed
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Abstract

Heart disease is one of the leading causes of death worldwide. Predicting and detecting heart disease early is crucial, as it allows medical professionals to take appropriate and necessary actions at earlier stages. Healthcare professionals can diagnose cardiac conditions more accurately by applying machine learning technology. This study aimed to enhance heart disease prediction using stacking and voting ensemble methods. Fifteen base models were trained on two different heart disease datasets. After evaluating various combinations, six base models were pipelined to develop ensemble models employing a meta-model (stacking) and a majority vote (voting). The performance of the stacking and voting models was…

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