A Gold Nanoparticles and MXene Nanocomposite Based Electrochemical Sensor for Point-of-Care Monitoring of Serum Biomarkers

The development of portable, cost-effective, and highly sensitive biosensors for real-time biomarker detection is crucial for advancing point-of-care testing (POCT) and wearable health monitoring. Here, we present an integrated portable electrochemical sensor (ip-ECS) that combines gold nanoparticles (AuNPs) and MXene-modified screen-printed electrodes (SPEs) with a custom-designed, low-power electronic system for point-of-care monitoring of serum biomarkers. The AuNPs and MXene nanocomposite significantly enhances the electrochemical performance of the SPE by providing a high density of active sites, improved conductivity, and catalytic activity. The detection of two model molecules (DA and UA) validated the…

• GM
  Guangzhou Medical University

  Awards: PX-66242684, 02-408-2203-2058
• GS
  Guangdong Science and Technology Department

  Award: 2023A1515110357
• GM
  Guangzhou Municipal Science and Technology Bureau

  Award: 202201011303