Tumor organoid-immune co-culture models: exploring a new perspective of tumor immunity

Recent advancements in technology have significantly expanded the scope of tumor research, progressing from the study of individual cells to more intricate tissue and organ-level analyses. Tumor organoids have emerged as a highly realistic platform for investigating tumor growth, development, and their interactions with the surrounding microenvironment. However, a notable limitation of these organoids is their lack of the diverse cellular composition typically observed in actual tumors, which hinders their ability to fully replicate the complexity of the tumor microenvironment. Immune cells play a pivotal role, and tumor immunology has become a major research hotspot. Research in tumor immunology aims to…

• JC
  Jiangsu Commission of Health

  Award: ZD2021039
• NN
  National Natural Science Foundation of China

  Awards: 82002591, 82072725
• CP
  China Postdoctoral Science Foundation

  Awards: 2021MD703958, 2020M670090ZX
• GO
  Government of Jiangsu Province
• NS
  Natural Science Foundation of Jiangsu Province

  Award: BK20200273