reviewJournal of Internal MedicineApr 24, 2025HYBRID OA

Gut microbiota development across the lifespan: Disease links and health‐promoting interventions

Örebro University · APC Microbiome Institute · +11 more institutions

PubMed
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Abstract

The gut microbiota plays a pivotal role in human life and undergoes dynamic changes throughout the human lifespan, from infancy to old age. During our life, the gut microbiota influences health and disease across life stages. This review summarizes the discussions and presentations from the symposium "Gut microbiota development from infancy to old age" held in collaboration with the Journal of Internal Medicine. In early infancy, microbial colonization is shaped by factors such as mode of delivery, antibiotic exposure, and milk-feeding practices, laying the foundation for subsequent increased microbial diversity and maturation. Throughout childhood and adolescence, microbial maturation continues, influencing…

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