Fluoroalkylacylsilanes as Novel Ambiphilic Donor–Acceptor Carbene Precursors

ConspectusCarbenes, as highly reactive intermediates, have emerged as pivotal tools in organic synthesis, catalysis, and materials science due to their versatile reactivity and broad applicability. Among the diverse classes of carbenes, donor–acceptor carbenes (DACs) have attracted significant attention owing to their unique electronic properties and exceptional reaction selectivity. The distinctive reactivity of DACs arises from the synergistic electronic interplay between electron-withdrawing and electron-donating groups attached to the carbene center, enabling a wide array of transformations. These attributes have established DACs as indispensable building blocks for constructing complex molecular…

• NN
  National Natural Science Foundation of China

  Award: 22471201
• NK
  National Key Research and Development Program of China

  Award: 2022YFA1506100
• SS
  Shenzhen Science and Technology Innovation Program

  Awards: JCYJ20230807090212023, JCYJ20220818100604009
• BA
  Basic and Applied Basic Research Foundation of Guangdong Province

  Award: 2023A1515010601