Advances in 3D-printed scaffold technologies for bone defect repair: materials, biomechanics, and clinical prospects
Nantong University · Affiliated Hospital of Nantong University
Abstract
The treatment of large bone defects remains a significant clinical challenge due to the limitations of current grafting techniques, including donor site morbidity, restricted availability, and suboptimal integration. Recent advances in 3D bioprinting technology have enabled the fabrication of structurally and functionally optimized scaffolds that closely mimic native bone tissue architecture. This review comprehensively examines the latest developments in 3D-printed scaffolds for bone regeneration, focusing on three critical aspects: (1) material selection and composite design encompassing metallic; (2) structural optimization with hierarchical porosity (macro/micro/nano-scale) and biomechanical properties…
Citation impact
- FWCI
- 38.59
- Percentile
- 100%
- References
- 216
Authors
5Topics & keywords
- Scaffold
- 3d printed
- Biomechanics
- Biomedical engineering
- Engineering
- Materials science
- Medicine
- Anatomy