The microbiologist's guide to metaproteomics

Bossche, Tim Van Den; Armengaud, Jean; Benndorf, Dirk; Blakeley‐Ruiz, J. Alfredo; Brauer, Madita; Cheng, Kai; Creskey, Marybeth; Figeys, Daniel; Grenga, Lucia; Griffin, Timothy J.; Henry, Céline; Hettich, Robert L.; Holstein, Tanja; Jagtap, Pratik; Jehmlich, Nico; Kim, Jonghyun; Kleiner, Manuel; Kunath, Benoît J.; Malliet, Xuxa; Martens, Lennart; Mehta, Subina; Mesuere, Bart; Ning, Zhibin; Tanca, Alessandro; Uzzau, Sergio; Verschaffelt, Pieter; Wang, Jing; Wilmes, Paul; Zhang, Xu; Zhang, Xin; Li, Leyuan; Initiative, The Metaproteomics

doi:10.1002/imt2.70031

reviewiMetaMay 6, 2025GOLD OA

The microbiologist's guide to metaproteomics

TVTim Van Den Bossche JAJean Armengaud DBDirk Benndorf JAJ. Alfredo Blakeley‐Ruiz MBMadita Brauer

Ghent University · VIB-UGent Center for Medical Biotechnology · +24 more institutions

PubMed

Indexed incrossrefdoajpubmed

Abstract

Metaproteomics is an emerging approach for studying microbiomes, offering the ability to characterize proteins that underpin microbial functionality within diverse ecosystems. As the primary catalytic and structural components of microbiomes, proteins provide unique insights into the active processes and ecological roles of microbial communities. By integrating metaproteomics with other omics disciplines, researchers can gain a comprehensive understanding of microbial ecology, interactions, and functional dynamics. This review, developed by the Metaproteomics Initiative (www.metaproteomics.org), serves as a practical guide for both microbiome and proteomics researchers, presenting key principles,…

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Topics & keywords

Topics

Keywords

Metaproteomics
Medicine
Medical physics
Chemistry
Metagenomics

UN Sustainable Development Goals

Life in Land

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