TIMER3: an enhanced resource for tumor immune analysis

The tumor immune microenvironment plays a critical role in tumor progression and immunotherapy response, with the abundance and composition of infiltrating immune cells serving as key determinants of therapeutic outcomes. Given the limitations of direct experimental methods, computational deconvolution algorithms are widely applied to infer immune cell infiltration from bulk RNA-seq data. While such estimates have proven valuable for studying tumor-immune interactions, large-scale, systematic analyses across multiple cancer types and treatment contexts remain limited. To address this need, we developed TIMER3 (https://compbio.cn/timer3/), an upgraded web server that substantially extends the functionality and…

• SU
  Sichuan University
• NS
  Natural Science Foundation of Sichuan Province

  Award: 2022NSFSC0054