articlenpj Digital MedicineMay 9, 2025GOLD OA

Evaluating large language model workflows in clinical decision support for triage and referral and diagnosis

Max Delbrück Center · Humboldt-Universität zu Berlin · +3 more institutions

PubMed
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Abstract

Accurate medical decision-making is critical for both patients and clinicians. Patients often struggle to interpret their symptoms, determine their severity, and select the right specialist. Simultaneously, clinicians face challenges in integrating complex patient data to make timely, accurate diagnoses. Recent advances in large language models (LLMs) offer the potential to bridge this gap by supporting decision-making for both patients and healthcare providers. In this study, we benchmark multiple LLM versions and an LLM-based workflow incorporating retrieval-augmented generation (RAG) on a curated dataset of 2000 medical cases derived from the Medical Information Mart for Intensive Care database. Our…

Citation impact

82
total citations
FWCI
153.57
Percentile
100%
References
33
Citations per year

Authors

8

Topics & keywords

Keywords
  • Medical diagnosis
  • Triage
  • Workflow
  • Referral
  • Decision support system
  • Health care
  • Clinical decision making
  • Clinical decision support system
UN Sustainable Development Goals
  • Peace, Justice and strong institutions
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Funding