Transparency in the Reporting of Artificial Intelligence – The TITAN Guideline

The use of AI in research and the literature is increasing. The need for transparency is clear. Here we present a guideline to transparently report the use of AI in any manuscript in general. The guideline items cover; declaration, purpose and scope, AI tools and configuration, data inputs and safeguards, human oversight and verification, bias, ethics and regulatory compliance and reproducibility and transparency. These items have been confirmed in a recent Delphi consensus exercise with high participation and agreement. This guide will evolve over time as technology, systems and behaviour evolve.