Analytical Green Star Area (AGSA) as a new tool to assess greenness of analytical methods

The field of Green Chemistry (GC) and Green Analytical Chemistry (GAC) has led to the development of multiple metrics designed to assess the impact of analytical methods. Among these, the Analytical Eco-Scale (AES) provides a quantitative evaluation but lacks visual representation, limiting intuitive assessment. The Green Analytical Procedure Index (GAPI) and its variant offer graphical evaluation, yet they lack a total scoring system, making direct comparisons difficult. While ModifiedGAPI (MoGAPI) and ComplexMoGAPI provide a total score for each method, their assessment is not directly structured around the principles of GAC, relying instead on 16 and 27 predefined questions, respectively. In contrast, the…