reviewJournal of NanobiotechnologyMay 28, 2025GOLD OA

“Double-sided protector” Janus hydrogels for skin and mucosal wound repair: applications, mechanisms, and prospects

Central South University · Changsha Medical University · +5 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Skin and mucous membranes serve as crucial barrier tissues within the human body. Defective wound healing not only inflicts pain but also heightens the risk of infection and impairs immune function. Janus hydrogels possess two-sided distinct asymmetric structures that endow them with diverse properties such as high water absorbency, flexibility, anti-adhesion ability etc. These hydrogels also exhibit great potential in biofluid transport, drug delivery and promoting tissue repair. Currently, research efforts predominantly concentrate on the preparation techniques, properties, and biomedical applications. This review summarized its structural characteristics and different forms of designations, and focused on…

Citation impact

64
total citations
FWCI
49.59
Percentile
100%
References
138
Citations per year

Authors

8

Topics & keywords

Keywords
  • Self-healing hydrogels
  • Janus
  • Wound healing
  • Chemistry
  • Nanotechnology
  • Medicine
  • Materials science
  • Surgery
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