articleJournal of Trace Elements and MineralsMay 29, 2025GOLD OA

Nanotoxicity unveiled: Evaluating exposure risks and assessing the impact of nanoparticles on human health

Indian Veterinary Research Institute · Sharda University · +2 more institutions

Indexed incrossrefdoaj

Abstract

• This review explores the dual-edged nature of nanotechnology, showcasing its significant health risks to human health and the environment. • It emphasizes how nanoparticles can induce reactive oxygen species, triggering oxidative stress, inflammation, and disturbances in cellular antioxidant defenses. • Fundamental physicochemical properties like size, shape, and surface charge are discussed for their critical role in determining nanoparticle toxicity. • The paper also highlights nanoparticles’ ability to cross physiological barriers, potentially accumulating in various organs and associated toxicities. • This paper discusses various methods for assessing toxicity and examines the current landscape of…

Citation impact

53
total citations
FWCI
21.31
Percentile
100%
References
190
Citations per year

Authors

7

Topics & keywords

Keywords
  • Nanotoxicology
  • Human health
  • Risk assessment
  • Environmental health
  • Risk analysis (engineering)
  • Nanotechnology
  • Nanoparticle
  • Medicine
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