High diversity of dietary flavonoid intake is associated with a lower risk of all-cause mortality and major chronic diseases

Higher habitual intakes of dietary flavonoids have been linked with a lower risk of all-cause mortality and major chronic disease. Yet, the contribution of diversity of flavonoid intake to health outcomes remains to be investigated. Here, using a cohort of 124,805 UK Biobank participants, we show that participants who consumed the widest diversity of dietary flavonoids, flavonoid-rich foods and/or specific flavonoid subclasses had a 6-20% significantly lower risk of all-cause mortality and incidence of cardiovascular disease, type 2 diabetes, cancer, respiratory disease and neurodegenerative disease. Furthermore, we report that both quantity and diversity of flavonoids are independent predictors of mortality…

• WT
  Wellcome Trust
• DO
  Department of Agriculture, Environment and Rural Affairs, UK Government
• UR
  UK Research and Innovation

  Award: 22/CC/11147
• DF
  Department for the Economy
• BH
  British Heart Foundation
• NR
  Northwest Regional Development Agency
• MR
  Medical Research Council
• NH
  National Health and Medical Research Council

  Award: APP1159914