Cellular Redox Regulation and Fluorescence Imaging

Cellular redox homeostasis governs numerous essential biological processes and presents broad implications in human health and diseases. Cells maintain the redox homeostasis by expression of some types of oxidants, reductants, and redox-active metals, while processing elaborate mechanisms to regulate their internal redox status. These biomolecules can serve as biomarkers to identify the alterations in redox status. The cellular redox dysregulation indicates a crucial pathogenic mechanism in conditions such as inflammatory diseases, cancer, and neurodegenerative disorders. Consequently, exploring the self-regulatory mechanisms of cellular redox homeostasis and in situ imaging of redox changes have emerged as…

• NN
  National Natural Science Foundation of China

  Awards: 22174089, 22204093, 22374093, 22276115, 22404099, 22134004
• NS
  Natural Science Foundation of Shandong Province

  Awards: ZR2024MB046, 2024HWYQ-014, 2023HWYQ-075
• TS
  Taishan Scholar Project of Shandong Province

  Award: tsqn.202312336