articleMolecular CellJul 1, 2025Closed access

MLKL activates the cGAS-STING pathway by releasing mitochondrial DNA upon necroptosis induction

ZDZhangcheng DingRWRui WangYLYuhua LiXWXiaodong Wang

National Institute of Biological Sciences, Beijing · Tsinghua University

PubMed
Indexed incrossrefpubmed

Abstract

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47
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FWCI
28.73
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100%
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81
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4

Topics & keywords

Topics
Keywords
  • Necroptosis
  • Biology
  • Cell biology
  • Sting
  • Mitochondrial DNA
  • Mitochondrion
  • Virology
  • Programmed cell death
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