articleThe Journal of Clinical Endocrinology & MetabolismJul 14, 2025Closed access

Primary Aldosteronism: An Endocrine Society Clinical Practice Guideline

Brigham and Women's Hospital · Harvard University · +18 more institutions

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Abstract

Background

Primary aldosteronism (PA), a primary adrenal disorder leading to excessive aldosterone production by one or both adrenal glands, is a common cause of hypertension. It is associated with an increased risk of cardiovascular complications compared with primary hypertension. Despite effective methods for diagnosing and treating PA, it remains markedly underdiagnosed and undertreated.

Objective

To develop an updated guideline that provides a practical, clinical approach to identifying and managing PA to improve diagnosis rates and encourage targeted treatment.

Citation impact

204
total citations
FWCI
185.43
Percentile
100%
References
241
Citations per year

Authors

15

Topics & keywords

Keywords
  • Primary aldosteronism
  • Medicine
  • Guideline
  • Aldosterone
  • Secondary hypertension
  • Intensive care medicine
  • Grading (engineering)
  • Internal medicine
UN Sustainable Development Goals
  • Decent work and economic growth
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Funding