articleNatureJul 16, 2025HYBRID OA

Detecting structural heart disease from electrocardiograms using AI

Columbia University Irving Medical Center · New York Hospital Queens · +7 more institutions

PubMed
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Abstract

Early detection of structural heart disease is critical to improving outcomes, but widespread screening remains limited by the cost and accessibility of imaging tools such as echocardiography1,2. Recent advances in machine learning applied to heart rhythm recordings have shown promise in identifying disease3,4, although previous work has been limited by development in narrow populations or targeting only select heart conditions5. Here we introduce a deep learning model, EchoNext, trained on more than 1 million heart rhythm and imaging records across a large and diverse health system to detect many forms of structural heart disease. The model demonstrated high diagnostic accuracy in internal and external…

Citation impact

62
total citations
FWCI
68.15
Percentile
100%
References
36
Citations per year

Authors

50

Topics & keywords

Keywords
  • Medical diagnosis
  • Heart disease
  • Heart Rhythm
  • Artificial intelligence
  • Machine learning
  • Computer science
  • Disease
  • Medicine
UN Sustainable Development Goals
  • Good health and well-being
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