A comprehensive review of unlocking the potential of lignin-derived biomaterials: from lignin structure to biomedical application

Inspired by natural organisms, biomimetic materials with exceptional biocompatibility, degradability, and multifunctionality have emerged as promising candidates for biomedical applications. Lignin, a plant-derived organic polymer, has gained attention due to its intrinsic antioxidant activity, adhesive properties, and biocompatibility. Despite its structural advantages, challenges in stability, biodegradability, and practical implementation hinder its utilization. Structural modifications through chemical/physical treatments or microbial/enzymatic can optimize lignin's bioactivity, mechanical strength, and adhesion, enabling applications in drug delivery, Ultraviolet (UV) shielding, sensing, and wound…

• NN
  National Natural Science Foundation of China

  Award: 82304733
• CA
  Chinese Academy of Medical Sciences

  Awards: 2022-12M-2-001, 2022-12M-1-018
• QU
  Qinghai University

  Award: 2023-kyt-1
• JS
  Jilin Scientific and Technological Development Program

  Awards: 20230401102YY, 2022-I2M-2-002, 2021-I2M-1-022, 2022-I2M-2-001