reviewFood Science & NutritionJul 28, 2025HYBRID OA

Phenolic Compounds in Exercise Physiology: Dual Role in Oxidative Stress and Recovery Adaptation

Atatürk University · Ardahan University

PubMed
Indexed incrossrefpubmed

Abstract

Exercise-induced oxidative stress results from the overproduction of reactive oxygen and nitrogen species (ROS/RNS) during intense physical activity, potentially impairing muscle function and recovery. Phenolic compounds, abundant in plant-based foods, are known for their potent antioxidant properties and may modulate redox homeostasis in athletes. This review critically examines the dual role of phenolic compounds in exercise physiology, highlighting both their protective antioxidant effects and the risks of excessive intake that may disrupt adaptive responses. We provide an overview of their molecular mechanisms, dose-dependent outcomes, and bioavailability issues, alongside evidence from animal and human…

Citation impact

45
total citations
FWCI
35.19
Percentile
100%
References
154
Citations per year

Authors

2

Topics & keywords

Keywords
  • Oxidative stress
  • Antioxidant
  • Reactive oxygen species
  • Mitochondrial biogenesis
  • Bioavailability
  • Cellular adaptation
  • Nutraceutical
  • Pharmacology
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