Enhancing biosafety in photodynamic therapy: progress and perspectives
Ewha Womans University · Fuzhou University · +1 more institution
Abstract
Photodynamic therapy (PDT), a non-invasive method with minimal drug-resistance, high spatiotemporal selectivity, and involvement of reactive oxygen species (ROS) in phototherapy methods, plays an increasingly vital role in cancer treatment. Throughout the development of PDT, enhancing the therapeutic efficacy of photosensitizers (PSs) has been a consistent research focus. However, the continuous progress and widespread use of PDT have highlighted the importance of its safety. For instance, the significant side effects of PSs remain a notable issue, given that traditional PSs utilize an "always-ON" strategy, leading to severe phototoxic symptoms such as burning sensations, skin redness, and scabbing.…
Citation impact
- FWCI
- 34.52
- Percentile
- 100%
- References
- 159
Authors
7Topics & keywords
- Biosafety
- Photodynamic therapy
- Nanotechnology
- Medicine
- Intensive care medicine
- Engineering ethics
- Chemistry
- Engineering