articleAdvanced MaterialsAug 7, 2025HYBRID OA

Artificial Intelligence‐Driven Nanoarchitectonics for Smart Targeted Drug Delivery

University of Wollongong · Institute of Nanotechnology · +3 more institutions

PubMed
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Abstract

The development of data-driven and targeted drug delivery systems is essential for advancing precision therapeutics. Despite substantial progress in nanocarrier development, conventional platforms continue to face major challenges in clinical translation due to biological complexity, off-target accumulation, and limited adaptability to dynamic physiological environments. The integration of nanoarchitectonics and artificial intelligence (AI) offers an advanced strategy for engineering delivery systems that are structurally programmable, stimuli-responsive, and autonomously optimized. Nanoarchitectonics enables the construction of hierarchical nanostructures with precise spatial and temporal control, while AI…

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