The UCSC Genome Browser database: 2026 update

Casper, Jonathan D.; Speir, Matthew L; Raney, Brian J.; Perez, Gerardo; Nassar, Luis R; Lee, Christopher M.; Hinrichs, Angie S.; Gonzalez, Jairo Navarro; Fischer, Clay; Diekhans, Mark; Clawson, Hiram; Benet‐Pagès, Anna; Barber, Galt P; Vaske, Charles; Baren, Marijke J. van; Wang, Karen; Rodríguez, Y.; Jenkins-Kiefer, Jaidan Ashlyn; Chalamala, Megna; Haussler, David; Kent, William; Haeussler, Maximilian

doi:10.1093/nar/gkaf1250

articleNucleic Acids ResearchNov 18, 2025GOLD OA

The UCSC Genome Browser database: 2026 update

JDJonathan D. Casper MLMatthew L Speir BJBrian J. Raney GPGerardo Perez LRLuis R Nassar

University of California, Santa Cruz · Helmholtz Zentrum München · +1 more institution

PubMed

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Abstract

Now in its 25th year of operation, the UCSC Genome Browser (https://genome.ucsc.edu) provides a central location for researchers around the world to display and compare annotations on assembled genomes. Highlighted updates include a positional heatmap display, used to show data on functional consequences of mutation from MaveDB; QuickLift, a tool to copy annotation data seen on one assembly for display on another related assembly; and HubSpace, an initiative to simplify the process of creating and using track hubs by providing each user account with dedicated storage on UCSC's infrastructure.

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Topics & keywords

Topics

Keywords

Genome browser
Annotation
Genome
Process (computing)
Track (disk drive)
Mutation
Human genome

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