Halogen bonding in functional chiral systems
Shandong Normal University · Shandong University
Abstract
The halogen bond (XB) is a directional noncovalent interaction formed between a halogen atom acting as an electrophilic site and a Lewis base. In recent years, it has shown great potential in the design of functional chiral systems. Due to its tunable interaction strength and pronounced directionality, the XB is becoming a powerful tool for constructing and controlling chirality at both molecular and supramolecular levels. In functional chiral systems, XBs are widely employed to induce, amplify, and transfer chirality, primarily arising from the directionally anisotropic electronic distribution on the surfaces of iodine, bromine, or chlorine atoms. This strategy enables precise construction and stereocontrol…
Citation impact
- FWCI
- 68.79
- Percentile
- 100%
- References
- 289
Authors
2Topics & keywords
- Supramolecular chemistry
- Chirality (physics)
- Non-covalent interactions
- Density functional theory
- Electrophile
- Supramolecular chirality
- Molecule
- Halogen bond