articleFrontiers in Cell and Developmental BiologyJan 5, 2026GOLD OA

AI-driven biomaterial design: an intelligent closed loop from reverse design to biological response

Second Affiliated Hospital of Jilin University · Jilin University · +1 more institution

PubMed
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Abstract

Traditional approaches to biomaterial design face numerous challenges, including high trial-and-error costs, long development cycle, and the difficulty in deciphering the complex relationship between material properties and biological responses. With the rise of artificial intelligence (AI) technology, its capabilities in processing high-dimensional data and constructing complex mapping relationships have brought revolutionary changes to biomaterial design. This article reviews the four core applications of AI in the design of biomaterials. Firstly, based on the therapeutic needs of diseases, the functions of materials are clarified and formulations are generated. Secondly, high-throughput prediction and…

Citation impact

7
total citations
FWCI
41.46
Percentile
100%
References
106
Too recent for citation history.

Authors

9

Topics & keywords

Keywords
  • Biomaterial
  • Biocompatible material
  • Realization (probability)
  • Closed loop
  • Biological materials
  • Face (sociological concept)
UN Sustainable Development Goals
  • Industry, innovation and infrastructure
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