Kidney-targeted nanoplatforms: Strategies and applications

Renal diseases remain a major global health burden, with an estimated 850 million individuals affected by chronic kidney disease, acute kidney injury, glomerulonephritis, and diabetic nephropathy. These multifactorial diseases collectively account for substantial morbidity and mortality burdens. This grim trajectory demands urgent development of drugs that are capable of simultaneously enhancing renal efficacy while circumventing systemic toxicity. In response to this challenge, engineered nanoplatforms designed specifically for the treatment of kidney diseases have emerged as a promising solution. These nanoplatforms offer the unique ability to deliver targeted therapeutics directly to specific regions of the…

• NS
  Natural Science Foundation of Shanghai
• NK
  National Key Research and Development Program of China

  Award: 2022YFC2304700
• FR
  Fundamental Research Funds for the Central Universities

  Award: YG2023QNA04