articleVaccinesJan 5, 2026GOLD OA

The Yellow Fever Vaccine Journey: Milestones and Future Directions

SSShriyansh SrivastavaNJNandani JayaswalPGPranav GuptaSBSathvik Belagodu SridharPJPooja Jaiswal

Galgotias University · Deen Dayal Upadhyaya Gorakhpur University · +18 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Yellow fever, a mosquito-borne viral hemorrhagic disease, remains a significant public health concern in endemic regions of Africa and South America. The development of the yellow fever vaccine marked a milestone in virology and immunization. In the 1930s, Max Theiler created the 17D live-attenuated vaccine, a breakthrough that has achieved global recognition and continues to underpin prevention strategies. This review outlines the historical evolution of the yellow fever vaccine, highlighting pivotal scientific advances, technological innovations, and global eradication initiatives. It examines the current landscape of immunization, focusing on the World Health Organization's Eliminate Yellow Fever Epidemics…

Citation impact

4
total citations
FWCI
82.93
Percentile
99%
References
190
Too recent for citation history.

Authors

14

Topics & keywords

Keywords
  • Yellow fever
  • Milestone
  • Yellow fever vaccine
  • Public health
  • Vaccination
  • Global health
  • Outbreak
  • Zika virus
No related works found for this paper.

Funding