articleNature Reviews Gastroenterology & HepatologyJan 5, 2026Closed access

Acute-on-chronic liver failure: pathophysiological mechanisms and clinical management

SKS. K. SarinACAshok ChoudhuryAKAnupam KumarNMNadim MahmudGHG. H. Lee

Institute of Liver and Biliary Sciences · Hospital of the University of Pennsylvania · +7 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

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4
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FWCI
53.48
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100%
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222
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Authors

12

Topics & keywords

Topics
Keywords
  • Liver transplantation
  • Decompensation
  • Pathophysiology
  • Cirrhosis
  • Organ dysfunction
  • Liver disease
  • Immune system
  • Disease
UN Sustainable Development Goals
  • Good health and well-being
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