articleNature ImmunologyJan 7, 2026Closed access

Active aldehydes accelerate CD8+ T cell exhaustion by metabolic alteration in the tumor microenvironment

YHYasuharu HakuKKKoji KitaokaKIKoki IchimaruTHT HiranoJWJun Wang

Kyoto University · Shimadzu (Japan) · +1 more institution

PubMed
Indexed incrossrefpubmed

Abstract

No abstract available for this paper.

Citation impact

5
total citations
FWCI
58.02
Percentile
100%
References
76
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Authors

21

Topics & keywords

Topics
Keywords
  • Glycolysis
  • T cell
  • Mitochondrion
  • Anaerobic glycolysis
  • Metabolic pathway
  • Tumor microenvironment
  • Beta oxidation
  • Cell
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