articleBMJJan 6, 2026HYBRID OA

Effects of lifestyle interventions in pregnancy on gestational diabetes: individual participant data and network meta-analysis

University of Liverpool · Birmingham Women's Hospital · +44 more institutions

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Abstract

Abstract Objectives To assess the effects of lifestyle interventions on gestational diabetes, determine whether the effects vary by maternal body mass index, age, parity, ethnicity, education level, or intervention, and rank interventions by effectiveness. Design Individual participant data (IPD) and network meta-analysis. Data sources Major electronic databases (January 1990 to April 2025). Methods This meta-analysis included randomised trials on the effects of lifestyle interventions (physical activity based, diet based, or mixed) in pregnancy on gestational diabetes. Main outcomes were gestational diabetes defined by any criteria and by UK NICE (National Institute for Health and Care Excellence) criteria;…

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